It was not too long ago that an HIV diagnosis was read as a death sentence. In its earlier decades, the HIV/AIDS crisis was synonymous with fear and loss, steeped in stigma. Over recent years, open conversation and science have come together to combat this stigma while proactively paving the way for life-saving treatments and preventive measures like PrEP. Now, in 2026, with discreet and modern platforms that meet people where they’re at in their lives, HIV prevention has evolved from hushed words of warning into something far more sex-positive and accessible. Game-changing services like MISTR are a testament to this shift, showing our community that healthcare doesn’t have to feel clinical or shaming to work. It can be empowering and, dare I say,  celebratory.

Few people embody this evolution quite like Tristan Schukraft, founder of MISTR. With one hand in healthcare and the other high-fiving through queer nightlife, Schukraft gets that, from the bar to the bedroom and beyond,  prevention happens in person and in real life. His approach has helped turn PrEP, DoxyPEP, and testing into normalized parts of our daily queer life, reaching hundreds of thousands of people across the US.

In our conversation, Schukraft shares candidly about stigma, policy, and why the future of sexual health depends on keeping it real.

BLADE: You have one hand in healthcare and the other in nightlife and queer spaces. Can you share with us how these two spheres impact and inform each other? How do they impact and inform you? 

SCHUKRAFT: Honestly, for me, they’ve never been separate. Nightlife and queer spaces are where people meet, date, hook up, fall in love, and make friends. That’s real life. Being in queer spaces all the time keeps me grounded and reminds me who we’re building MISTR for. 

BLADE: MISTR markets sexual health in a sex-positive, stigma-free fashion. Can you share with us how you measure the impact of this approach? 

SCHUKRAFT: This year, we held the first-ever National PrEP Day.  Dua Lipa performed, and Cardi B was there.  After the event, Cardi B went on her Instagram live to encourage people to sign up for PrEP.  

When you make sexual health stigma-free and sex positive, people talk about it. We see it in how people use the platform. When 700,000 people are willing to sign up, get tested, start PrEP, and add things like DoxyPEP, that tells us we’ve made it feel safe and normal instead of scary or awkward. And then we see it in the results. Since we expanded DoxyPEP, STI positivity among our patients dropped by half.  

BLADE: How have you seen the conversation of sexual health in our LGBTQ+ community change in mainstream culture in recent years? 

SCHUKRAFT: Ten years ago, nobody was casually talking about PrEP, and if they did, it likely referenced one being a Truvada whore. Now it’s part of the culture. Popstars like Troye Sivan post pictures of their daily PrEP pill on social media. Cardi B goes on Instagram Live telling people to get on PrEP.  

For many sexually active gay men, taking PrEP is simply part of the gay experience.  For people in more remote areas, it might not be as talked about. Particularly in rural or more conservative places, MISTR can be a life-changing option. No awkward visits to the family doctor or the local pharmacy where everybody knows your business. It’s all done discreetly online and shipped straight to your door. 

BLADE: You have publicly argued that cuts to government HIV prevention funding are of high risk. Would you please elaborate for us on what those budget decisions mean on an individual level? 

SCHUKRAFT: It means real people fall through the cracks. Someone doesn’t get tested. Someone waits too long to start PrEP. Someone finds out they’re HIV-positive later than they should have. Community clinics will be the hardest hit, especially those in underserved communities. The good news is that MISTR is ready to help people who might lose their access to care. All you need to do is sign up at mistr.com, and it’s totally free with or without insurance. 

BLADE: From your (and MISTR’s) perspective, how do these funding cuts threaten ongoing efforts to end the HIV epidemic? 

SCHUKRAFT: For the first time, we have all the tools to end HIV. If everybody who is HIV negative is taking PrEP and everyone HIV+ is virally suppressed, we can end all new HIV transmissions in the United States.  We have everything we need today.  All we need is to get more people on PrEP. Cutting funding risks losing that momentum. Ending HIV requires scale and consistency. Every time funding gets cut, you lose momentum, trust, and infrastructure, and rebuilding that takes years. 

HIV transmissions don’t pause because budgets change. 

BLADE: In our current climate of decreased federal investment, what role do you feel private healthcare and business should play in sexual health? 

SCHUKRAFT: With reports that the current administration is considering cuts to HIV and prevention funding,  we face a moment of reckoning. At the same time, some employers are seeking to exclude PrEP and HIV prevention from their coverage on religious freedom grounds. If these challenges succeed, and if federal funding is slashed, the consequences for public health will be devastating. But this is where the private sector must step up to fill the gap, bridge divides, and deliver results. 

Businesses have the power and platform to normalize HIV prevention and drive measurable outcomes. At MISTR, we see firsthand what’s possible: since introducing DoxyPEP, STI positivity rates among our patients have been cut in half. But it’s not just about medication. It’s about messaging.  

Our sex-positive, stigma-free marketing speaks directly to our community, making sexual health part of everyday life. No awkward doctor visits, no needles, no paperwork — just free online PrEP and STI testing, prescribed by real physicians and delivered to your door. That kind of impact could grow exponentially if more employers embraced this approach and made HIV prevention part of their employee wellness programs. 

Employers, this is your call to action. Start by making sure your health plans cover PrEP and DoxyPEP. Partner with platforms like MISTR to give employees private, stigma-free access to care. Offer on-site testing. Talk openly about sexual health, not just during Pride, but every day of the year. This is not political — this is about protecting lives, strengthening communities, and building a healthier, more productive workforce. Because healthy employees aren’t just good for public health — they’re good for business. 

When the private sector steps up, outcomes improve. And when businesses align with platforms like MISTR, scaling impact isn’t just possible — it’s happening. 

BLADE: Has MISTR experienced any direct effects from these recent shifts in public health funding? 

SCHUKRAFT: MISTR’s unique model is totally free for patients with or without insurance, and we don’t cost the government or taxpayers a penny. We are scaling up our efforts to reach people who might be losing their access or care. 

BLADE: What would be your message to policymakers who are considering further cuts to HIV/AIDS programs? 

SCHUKRAFT: During his first term, President Donald Trump committed unprecedented resources to the Ending the HIV Epidemic initiative here at home. Bipartisan support has shown what’s possible when bold leadership meets smart strategy. To policymakers: I urge you to reconsider any cuts to HIV prevention funding. This is not the time to pull back. It’s the time to push forward. Ending HIV is within reach — but only if government, private industry, and community organizations stand together. 

BLADE: What is one perhaps overlooked win from last year that impacted you on a personal level? 

SCHUKRAFT: Seeing our STI positivity rate drop by half after expanding DoxyPEP. 

BLADE: Looking at the year ahead, what are MISTR’s most significant priorities for sexual health in 2026? 

SCHUKRAFT: Expanding access, especially in the South and in communities that still get left out. Rolling out injectable PrEP. And just continuing to make sexual healthcare easier and more normal. 

The 2026 Mr. Mid-Atlantic Leather competition was held at the Hyatt Regency Capitol Hill on Sunday. Seven contestants vied for the title and Gage Ryder was named the winner.

(Washington Blade photo by Michael Key)

‘Antony & Cleopatra’
Through Jan. 25
Synetic Theater at
Shakespeare Theatre Company’s Klein Theatre
450 7th St., N.W.
Synetictheater.org

A spectacle of operatic proportions, Synetic Theater’s “Antony & Cleopatra” is performed entirely voiceless. An adaptation of the Bard’s original (a play bursting with wordplay, metaphors, and poetic language), the celebrated company’s production doesn’t flinch before the challenge. 

Staged by Paata Tsikurishvili and choreographed by Irina Tsikurishvili, this worthy remount is currently playing at Shakespeare Theatre Company’s Klein Theatre, the same venue where it premiered 10 years ago. Much is changed, including players, but the usual inimitable Synectic energy and ingenuity remain intact.  

As audiences file into the Klein, they’re met with a monumental pyramid bathed in mist on a dimly lit stage. As the lights rise, the struggle kicks off: Cleopatra (Irina Kavsadze) and brother Ptolemy (Natan-Maël Gray) are each vying for the crown of Egypt. Alas, he wins and she’s banished from Alexandria along with her ethereal black-clad sidekick Mardian (Stella Bunch); but as history tells us, Cleopatra soon makes a triumphant return rolled in a carpet.  

Meanwhile, in the increasingly dangerous Rome, Caesar (memorably played by Tony Amante) is assassinated by a group of senators. Here, his legendary Ides of March murder is rather elegantly achieved by silver masked politicians, leaving the epic storytelling to focus on the titular lovers. 

The fabled couple is intense. As the Roman general Antony, Vato Tsikurishvili comes across as equal parts warrior, careerist, and beguiled lover. And despite a dose of earthiness, it’s clear that Kavsadze’s Cleopatra was born to be queen.

Phil Charlwood’s scenic design along with Colin K. Bills’ lighting cleverly morph the huge pyramidic structure into the throne of Egypt, the Roman Senate, and most astonishingly as a battle galley crashing across the seas with Tsikurishvili’s Antony ferociously at the helm.

There are some less subtle suggestions of location and empire building in the form of outsized cardboard puzzle pieces depicting the Mediterranean and a royal throne broken into jagged halves, and the back-and-forth of missives.

Of course, going wordless has its challenges. Kindly, Synectic provides a compact synopsis of the story. I’d recommend coming early and studying that page. With changing locations, lots of who’s who, shifting alliances, numerous war skirmishes, and lack of dialogue, it helps to get a jump on plot and characters.

Erik Teague’s terrific costume design is not only inspired but also helpful. Crimson red, silver, and white say Rome; while all things Egyptian have a more exotic look with lots of gold and diaphanous veils, etc. 

When Synetic’s voicelessness works, it’s masterful. Many hands create the magic: There’s the direction, choreography, design, and the outrageously committed, sinewy built players who bring it to life through movement, some acrobatics, and the remarkable sword dancing using (actual sparking sabers) while twirling to original music composed by Konstantine Lortkipanidze.

Amid the tumultuous relationships and frequent battling (fight choreography compliments of Ben Cunis), moments of whimsy and humor aren’t unwelcome. Ptolemy has a few clownish bits as Cleopatra’s lesser sibling. And Antony’s powerful rival Octavian (ageless out actor Philip Fletcher) engages in peppy propaganda featuring a faux Cleopatra (played by Maryam Najafzada) as a less than virtuous queen enthusiastically engaged in an all-out sex romp. 

When Antony and Cleopatra reach their respective ends with sword and adder, it comes almost as a relief. They’ve been through so much. And from start to finish, without uttering a word, Kavsadze and Tsikurishvili share a chemistry that pulls the audience into the grips of the doomed lovers’ palpable passion.